HORDB
A database of peptide hormones
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Protein Information
ID:
hd00051
Active Ingredients:
Afamelanotide
DRUGBANK Accession Number:
DB04931
Active Sequence:
Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Sequence Length:
13
Type:
Small Molecule
Description:
AfamelanotideĀ is an injectable subcutaneous implant used to mitigate phototoxicity secondary to erythropoietic protoporphyria (EPP).
Disease:
EPP
CAS:
75921-69-6
SMILES:
CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
Drug Information
Drug Name
Strength
Dosage Form/Route
Company
Marketing Status
Approval year
Eptifibatide
0.75mg/1mL
INJECTION; SUSPENSION
Teva Parenteral Pharmaceuticals,LIc
Discontinued
2013