General Information

  • ID:  hor006876
  • Uniprot ID:  P01574??23-187)
  • Protein name:  Interferon beta
  • Gene name:  IGF1; IBP1;
  • Organism:  Homo sapiens
  • Family:  Alpha/beta interferon family
  • Source:  Human
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
  • GO MF:  GO:0005576 extracellular region; GO:0005615 extracellular space
  • GO BP:  GO:0008811 chloramphenicol O-acetyltransferase activity; GO:0005125 cytokine activity; GO:0005126 cytokine receptor binding; GO:0005132 type I interferon receptor binding
  • GO CC:  GO:0060337 type I interferon-mediated signaling pathway; GO:2000552 negative regulation of T-helper 2 cell cytokine production; GO:0045944 positive regulation of transcription by RNA polymerase II; GO:0140123 negative regulation of Lewy body formation; GO:0045071 negative regulation of viral genome replication; GO:0045581 negative regulation of T cell differentiation; GO:0002286 T cell activation involved in immune response; GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein; GO:0043330 response to exogenous dsRNA; GO:0045343 regulation of MHC class I biosynthetic process; GO:0070050 neuron cellular homeostasis; GO:0002323 natural killer cell activation involved in immune response; GO:0045089 positive regulation of innate immune response; GO:0009615 response to virus; GO:0030101 natural killer cell activation; GO:0098586 cellular response to virus; GO:0006959 humoral immune response; GO:0051607 defense response to virus; GO:0019221 cytokine-mediated signa

Sequence Information

  • Sequence:  SYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
  • Length:  165
  • Propeptide:  MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
  • Signal peptide:  MTNKCLLQIALLLCFSTTALS
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    NA

Physical Information

Mass: Formula:
Absent amino acids: Common amino acids:
pI: Basic residues:
Polar residues: Hydrophobic residues:
Hydrophobicity: Boman Index:
Half-Life: Half-Life Yeast:
Half-Life E.Coli: Aliphatic Index
Instability Index: Extinction Coefficient cystines:
Absorbance 280nm:

Literature

  • PubMed ID:  NA
  • Title:  NA