HORDB

ID: hor006667
Uniprot ID: Q5JQD4
Protein name: Peptide YY
Gene name: PYY3
Organism: Homo sapiens (Human)
Family: NPY family
Source: Human
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Homo (genus), Homininae (subfamily), Hominidae (family), Hominoidea (superfamily), Catarrhini (parvorder), Simiiformes (infraorder), Haplorrhini (suborder), Primates (order), Euarchontoglires (superorder), Boreoeutheria, Eutheria, Theria, Mammalia (class), Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity; GO:0031841 neuropeptide Y receptor binding
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0007631 feeding behavior
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: MVSVCRPWPAVAIALLALLVCLGALVDTCPIKPEAPGEDESLEELSHYYASLCHYLNVVTRQWWEGADMW
Length: 70(1-70)
Propeptide: MVSVCRPWPAVAIALLALLVCLGALVDTCPIKPEAPGEDESLEELSHYYASLCHYLNVVTRQWWEGADMW
Signal peptide: MVSVCRPWPAVAIALLALLVCLG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-Q5JQD4-F1.pdb

hor006667_AF2.pdb

hor006667_ESM.pdb

Mass:	906307	Formula:	C356H541N87O100S6
Absent amino acids:	F	Common amino acids:	L
pI:	4.17	Basic residues:	5
Polar residues:	17	Hydrophobic residues:	31
Hydrophobicity:	36.43	Boman Index:	-1931
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	107.29
Instability Index:	4844.14	Extinction Coefficient cystines:	26720
Absorbance 280nm:	387.25