General Information

  • ID:  hor006661
  • Uniprot ID:  Q26492
  • Protein name:  Ion transport peptide-like
  • Gene name:  NA
  • Organism:  Schistocerca gregaria (Desert locust) (Gryllus gregarius)
  • Family:  Arthropod CHH/MIH/GIH/VIH hormone family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:   Schistocerca (genus), Cyrtacanthacridinae (subfamily), Acrididae (family), Acridoidea (superfamily), Acridomorpha , Acrididea (infraorder), Caelifera (suborder), Orthoptera (order), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia , Insecta (class), Hexapoda (subphylum), Pancrustacea , Mandibulata , Arthropoda (phylum), Panarthropoda , Ecdysozoa , Protostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
  • GO MF:  GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  SFFDIQCKGVYDKSIFARLDRICEDCYNLFREPQLHSLCRKDCFTSDYFKGCIDVLLLQDDMDKIQSWIKQIHGAEPGV
  • Length:  79(56-134)
  • Propeptide:  MHHQKQQQQQKQQGEAPCRHLQWRLSGVVLCVLVVASLVSTAASSPLDPHHLAKRSFFDIQCKGVYDKSIFARLDRICEDCYNLFREPQLHSLCRKDCFTSDYFKGCIDVLLLQDDMDKIQSWIKQIHGAEPGV
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  7-43; 23-39; 26-52
  • Structure ID:  AF-Q26492-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor006661_AF2.pdbhor006661_ESM.pdb

Physical Information

Mass: 1066215 Formula: C413H632N108O121S7
Absent amino acids: Common amino acids: D
pI: 5.02 Basic residues: 12
Polar residues: 20 Hydrophobic residues: 26
Hydrophobicity: -26.08 Boman Index: -14564
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 82.66
Instability Index: 2726.96 Extinction Coefficient cystines: 10345
Absorbance 280nm: 132.63

Literature

  • PubMed ID:  8786332
  • Title:  Locust ion transport peptide (ITP): primary structure, cDNA and expression in a baculovirus system.