HORDB

ID: hor006647
Uniprot ID: P70074
Protein name: GnRH-associated peptide 1
Gene name: gnrh1
Organism: Pagrus major (Red sea bream) (Chrysophrys major)
Family: GnRH family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Pagrus (genus), Sparidae (family), Spariformes (order), Eupercaria, Percomorphaceae, Euacanthomorphacea, Acanthomorphata, Ctenosquamata, Eurypterygia, Neoteleostei, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005183 gonadotropin hormone-releasing hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: DLDSLSDTLGDIIERFPHADSPCSVLGCAEEPPFPKMYRMKGFIGSGTDRDNGHRTYKK
Length: 59(37-95)
Propeptide: MAPQTSNLWLLLVVMMVMSQGCCQHWSYGLSPGGKRDLDSLSDTLGDIIERFPHADSPCSVLGCAEEPPFPKMYRMKGFIGSGTDRDNGHRTYKK
Signal peptide: MAPQTSNLWLLLVVMMVMSQGCC
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006647_AF2.pdb

hor006647_ESM.pdb

Mass:	760808	Formula:	C285H442N80O91S4
Absent amino acids:	QW	Common amino acids:	DG
pI:	5.61	Basic residues:	10
Polar residues:	19	Hydrophobic residues:	13
Hydrophobicity:	-74.41	Boman Index:	-14036
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	54.58
Instability Index:	4780.68	Extinction Coefficient cystines:	3105
Absorbance 280nm:	53.53