HORDB

ID: hor006604
Uniprot ID: O42241
Protein name: Progonadoliberin-2
Gene name: gnrh2
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Family: GnRH family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Oncorhynchus (genus), Salmoninae (subfamily), Salmonidae (family), Salmoniformes (order), Protacanthopterygii, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: QHWSHGWYPGGKRELDSFTTSEISEGIKLCEAEGCSYLRPQRRNILKNVILDALAREFQKRK
Length: 62(25-86)
Propeptide: MVSVARLVFMLGPLLCLGAQLSSSQHWSHGWYPGGKRELDSFTTSEISEGIKLCEAEGCSYLRPQRRNILKNVILDALAREFQKRK
Signal peptide: MVSVARLVFMLGPLLCLGAQLSSS
Modification: T1 Pyrrolidone carboxylic acid;T10 Glycine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006604_AF2.pdb

hor006604_ESM.pdb

Mass:	833645	Formula:	C320H504N96O93S2
Absent amino acids:	M	Common amino acids:	ELRGKS
pI:	9.31	Basic residues:	13
Polar residues:	18	Hydrophobic residues:	18
Hydrophobicity:	-84.52	Boman Index:	-16066
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	72.42
Instability Index:	6361.61	Extinction Coefficient cystines:	14105
Absorbance 280nm:	231.23