HORDB

ID: hor006451
Uniprot ID: P91797
Protein name: Molluscan insulin-related peptide 7 A chain
Gene name: NA
Organism: Lymnaea stagnalis (Great pond snail) (Helix stagnalis)
Family: Insulin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Lymnaea (genus), Lymnaeidae (family), Lymnaeoidea (superfamily), Hygrophila , Panpulmonata , Euthyneura , Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa , Spiralia , Protostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0030133 transport vesicle; GO:0031410 cytoplasmic vesicle

Sequence: EVMAEPSLVCDCCYNECSVRKLATYC
Length: 26(155-180)
Propeptide: MNASVESCLTFTFVLVALCVGLTIGQQVNTCTMFSRQHPRGLCGNRLARAHANLCFLLRNTYPDIFPRKRSVDNTFEKVYSIPLSVLAELDLSDDDWGAYVSKKDIPYRSETNGLSGANFESSAFDKQLELPAMKSTTSQLFRILKLRGSRLKREVMAEPSLVCDCCYNECSVRKLATYC
Signal peptide: MNASVESCLTFTFVLVALCVGLTIG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006451_AF2.pdb

hor006451_ESM.pdb

Mass:	337652	Formula:	C121H193N31O41S6
Absent amino acids:	FGHIQW	Common amino acids:	C
pI:	4.15	Basic residues:	2
Polar residues:	11	Hydrophobic residues:	7
Hydrophobicity:	22.31	Boman Index:	-3158
Half-Life:	1 hour	Half-Life Yeast:	30 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	71.15
Instability Index:	5021.92	Extinction Coefficient cystines:	3230
Absorbance 280nm:	129.2

PubMed ID: 8848162
Title: Expression and characterization of molluscan insulin-related peptide VII from the mollusc Lymnaea stagnalis.