HORDB

ID: hor006230
Uniprot ID: P56683
Protein name: Cardioactive peptide CAP23
Gene name: NA
Organism: Spodoptera eridania (Southern armyworm)
Family: GBP/PSP1/paralytic peptide family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Spodoptera (genus), Amphipyrinae (subfamily), Noctuidae (family), Noctuoidea (superfamily), Obtectomera , Ditrysia , Heteroneura (parvorder), Neolepidoptera (infraorder), Glossata (suborder), Lepidoptera (order), Amphiesmenoptera (superorder), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia , Insecta (class), Hexapoda (subphylum), Pancrustacea , Mandibulata , Arthropoda (phylum), Panarthropoda , Ecdysozoa , Protostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: NA
GO BP: NA
GO CC: NA

Function: Has excitatory effects on a semi-isolated heart from larval Manduca sexta, causing an inotropic effect at low concentrations of peptide and chronotropic and inotropic effects at high doses.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-P56683-F1.pdb

hor006230_AF2.pdb

hor006230_ESM.pdb

Mass:	291139	Formula:	C108H164N32O34S2
Absent amino acids:	HILMSW	Common amino acids:	GT
pI:	8.22	Basic residues:	3
Polar residues:	10	Hydrophobic residues:	5
Hydrophobicity:	-70.87	Boman Index:	-5195
Half-Life:	1 hour	Half-Life Yeast:	30 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	21.3
Instability Index:	821.74	Extinction Coefficient cystines:	1615
Absorbance 280nm:	73.41

PubMed ID: 10098624
Title: A cardioactive peptide from the southern armyworm, Spodoptera eridania.