HORDB

ID: hor005951
Uniprot ID: P13684
Protein name: Amphipathic peptide
Gene name: NA
Organism: Xenopus laevis (African clawed frog)
Family: Gastrin/cholecystokinin family
Source: animal
Expression: Expressed by the skin glands.
Disease: NA
Comments: NA
Taxonomy: Xenopus (subgenus), Xenopus (genus), Xenopodinae (subfamily), Pipidae (family), Pipoidea (superfamily), Anura (order), Batrachia (superorder), Amphibia (class), Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0006952 defense response; GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: GWASKIGQTLGKIAKVGLQGLMQPK
Length: 25(39-63)
Propeptide: MYKGIFLCVLFAVICANSLAKPSSDADEDNDEVERYVRGWASKIGQTLGKIAKVGLQGLMQPKREAMLRSAEAQGMIGTLTSKRIKQG
Signal peptide: MYKGIFLCVLFAVICANSLA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005951_AF2.pdb

hor005951_ESM.pdb

Mass:	303845	Formula:	C118H201N33O31S
Absent amino acids:	CDEFHNRY	Common amino acids:	G
pI:	11.28	Basic residues:	4
Polar residues:	7	Hydrophobic residues:	9
Hydrophobicity:	-8	Boman Index:	-315
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	97.6
Instability Index:	927.2	Extinction Coefficient cystines:	5500
Absorbance 280nm:	229.17

PubMed ID: 2830279
Title: Levitide, a neurohormone-like peptide from the skin of Xenopus laevis. Peptide and peptide precursor cDNA sequences.