HORDB

ID: hor005938
Uniprot ID: P08950
Protein name: Ranatensin
Gene name: NA
Organism: Lithobates pipiens (Northern leopard frog) (Rana pipiens)
Family: Bombesin/neuromedin-B/ranatensin family
Source: Animal
Expression: Expressed by the skin glands.
Disease: NA
Comments: NA
Taxonomy: Lithobates (genus), Ranidae (family), Ranoidea (superfamily), Neobatrachia (suborder), Anura (order), Batrachia (superorder), Amphibia (class), Tetrapoda , Dipnotetrapodomorpha , Sarcopterygii (superclass), Euteleostomi , Teleostomi , Gnathostomata , Vertebrata , Craniata (subphylum), Chordata (phylum), Deuterostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: NA
GO BP: GO:0006952 defense response; GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: QVPQWAVGHFM
Length: 11(48-58)
Propeptide: MTTIPAIGILPIDFLTILLLFSFISHSVCVEFAEDAGELDKSNAFRRQVPQWAVGHFMGKRSLSDDTEQATMYSSRFVESTS
Signal peptide: MTTIPAIGILPIDFLTILLLFSFISHS
Modification: T11 Methionine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005938_AF2.pdb

hor005938_ESM.pdb

Mass:	147807	Formula:	C61H86N16O14S
Absent amino acids:	CDEIKLNRSTY	Common amino acids:	QV
pI:	7.55	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	5
Hydrophobicity:	16.36	Boman Index:	275
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	61.82
Instability Index:	644.55	Extinction Coefficient cystines:	5500
Absorbance 280nm:	550

PubMed ID: 2458345
Title: Molecular cloning of cDNAs encoding the human bombesin-like peptide neuromedin B. Chromosomal localization and comparison to cDNAs encoding its amphibian homolog ranatensin.