HORDB

ID: hor005847
Uniprot ID: Q17093
Protein name: LWamide II
Gene name: NA
Organism: Anemonia sulcata (Mediterranean snakelocks sea anemone)
Family: LWamide neuropeptide family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Anemonia (genus), Actiniidae (family), Actiniaria (order), Hexacorallia (subclass), Anthozoa (class), Cnidaria (phylum), Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: QHPGLW
Length: 6(66-71)
Propeptide: KRQQPGLWGRSADPQQAGLWGKRQQPGLWGRSADPQQAGLWGKRQNPGLWGRSADPQQAGLWGKRQHPGLWGRSADPQQAGLWGRSAGSGKRQERIGIWGRSAEPPQYKELEDLKQKSAIPKAKPQ
Signal peptide: NA
Modification: T6 Tryptophan amide
Glycosylation: NA
Mutagenesis: NA

Function: Metamorphosin A may be part of an internal signaling system involved in control of metamorphosis.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005847_AF2.pdb

hor005847_ESM.pdb

Mass:	82620	Formula:	C35H48N10O8
Absent amino acids:	ACDEFIKMNRSTVY	Common amino acids:	GHLPQW
pI:	7.55	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	-96.67	Boman Index:	-201
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	65
Instability Index:	4300	Extinction Coefficient cystines:	5500
Absorbance 280nm:	1100