HORDB

ID: hor005712
Uniprot ID: Q9DGK7
Protein name: Neuropeptide Y
Gene name: npy
Organism: Cyprinus carpio (Common carp)
Family: NPY Family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Cyprinus (genus), Cyprininae (subfamily), Cyprinidae (family), Cyprinoidei (suborder), Cypriniformes (order), Cypriniphysae (superorder), Otophysi, Ostariophysi (subcohort), Otomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: YPTKPDNPGEDAPAEELAKYYSALRHYINLITRQRY
Length: 36(29-64)
Propeptide: MHPNMKMWIGWAACAFLLFACLGTLTEGYPTKPDNPGEDAPAEELAKYYSALRHYINLITRQRYGKRSSADTLISDLLIGETESHPQTRYEDHLVW
Signal peptide: MHPNMKMWIGWAACAFLLFACLGTLTEG
Modification: T36 Tyrosine amide
Glycosylation: NA
Mutagenesis: NA

Function: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005712_AF2.pdb

hor005712_ESM.pdb

Mass:	487919	Formula:	C192H290N52O58
Absent amino acids:	CFMVW	Common amino acids:	Y
pI:	7.51	Basic residues:	6
Polar residues:	11	Hydrophobic residues:	9
Hydrophobicity:	-112.22	Boman Index:	-9367
Half-Life:	2.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	2 min	Aliphatic Index	65.28
Instability Index:	6076.11	Extinction Coefficient cystines:	7450
Absorbance 280nm:	212.86