HORDB

ID: hor005682
Uniprot ID: P28674
Protein name: C-flanking peptide of NPY
Gene name: npy
Organism: Torpedo marmorata (Marbled electric ray)
Family: NPY family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Torpedo (genus), Torpedinidae (family), Torpediniformes (order), Batoidea (superorder), Elasmobranchii (subclass), Chondrichthyes (class), Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: SSPEALMMTDLMLRENAESFPKYRYDEPFMW
Length: 31(68-98)
Propeptide: MQTNMKFWLGVFTFAFCMLICIGTFADAYPSKPDNPGEGAPAEDLAKYYSALRHYINLITRQRYGKRSSPEALMMTDLMLRENAESFPKYRYDEPFMW
Signal peptide: MQTNMKFWLGVFTFAFCMLICIGTFADA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Function: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005682_AF2.pdb

hor005682_ESM.pdb

Mass:	432158	Formula:	C169H250N40O51S4
Absent amino acids:	CGHIQV	Common amino acids:	EM
pI:	4.1	Basic residues:	3
Polar residues:	7	Hydrophobic residues:	8
Hydrophobicity:	-66.45	Boman Index:	-6369
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	44.19
Instability Index:	6462.9	Extinction Coefficient cystines:	8480
Absorbance 280nm:	282.67

PubMed ID: 1549597
Title: Strong evolutionary conservation of neuropeptide Y: sequences of chicken, goldfish, and Torpedo marmorata DNA clones.