HORDB

ID: hor005658
Uniprot ID: Q9I9D3
Protein name: C-flanking peptide of NPY
Gene name: npy
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Family: NPY family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ictalurus (genus), Ictaluridae (family), Siluroidei (suborder), Siluriformes (order), Characiphysae (superorder), Otophysi, Ostariophysi (subcohort), Otomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: SNTDVLTPDLLFGEAEIRLQSRYDDPLMG
Length: 29(67-95)
Propeptide: MRPRANVCVGWAACILLVVCLCVLAEGYPTKPENPGEDAPVEELAKYYSALRHYINLITRQRYGKRSNTDVLTPDLLFGEAEIRLQSRYDDPLMG
Signal peptide: MRPRANVCVGWAACILLVVCLCVLAEG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Function: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Mechanism: NA
Cross BBB: NA
Target: npy2r
Target Unid: A0A2D0QDQ4
IC50: NA
EC50: NA
ED50: NA
Kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005658_AF2.pdb

hor005658_ESM.pdb

Mass:	376625	Formula:	C142H225N37O49S
Absent amino acids:	CHKW	Common amino acids:	L
pI:	3.79	Basic residues:	2
Polar residues:	8	Hydrophobic residues:	9
Hydrophobicity:	-38.28	Boman Index:	-6002
Half-Life / Aliphatic Index:	1.9 hour	Aliphatic Index:	94.14
Instability Index:	4676.9	Extinction Coefficient cystines:	1490
Absorbance 280nm:	53.21