HORDB

ID: hor005640
Uniprot ID: Q27441
Protein name: C-flanking peptide of NPY
Gene name: NPY
Organism: Aplysia californica (California sea hare)
Family: NPY family
Source: Animal
Expression: Highly expressed in the abdominal ganglion, to lesser extent in the pleural-pedal ganglion and much lower in the cerebral ganglion.
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: GKRGDSFRKREFFRTNGERYPEDAAAWTEFQ
Length: 31(62-92)
Propeptide: MQRVILVVLLLSCMAVLSVRADNSEMLAPPPRPEEFTSAQQLRQYLAALNEYYSIMGRPRFGKRGDSFRKREFFRTNGERYPEDAAAWTEFQ
Signal peptide: MQRVILVVLLLSCMAVLSVRA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Function: May play a role in the regulation of viscermotor functions during egg laying.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005640_AF2.pdb

hor005640_ESM.pdb

Mass:	428832	Formula:	C166H243N51O50
Absent amino acids:	CHILMV	Common amino acids:	R
pI:	9.25	Basic residues:	7
Polar residues:	8	Hydrophobic residues:	8
Hydrophobicity:	-157.74	Boman Index:	-12874
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	9.68
Instability Index:	3404.84	Extinction Coefficient cystines:	6990
Absorbance 280nm:	233