HORDB

ID: hor005494
Uniprot ID: Q5JQD4
Protein name: Putative peptide YY-3
Gene name: PYY3
Organism: Homo sapiens (Human)
Family: NPY family
Source: Human
Expression: NA
Disease: NA
Comments: Could be the product of a pseudogene.
Taxonomy: Homo (genus), Homininae (subfamily), Hominidae (family), Hominoidea (superfamily), Catarrhini (parvorder), Simiiformes (infraorder), Haplorrhini (suborder), Primates (order), Euarchontoglires (superorder), Boreoeutheria, Eutheria, Theria, Mammalia (class), Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity; GO:0031841 neuropeptide Y receptor binding
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0007631 feeding behavior
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: ALVDTCPIKPEAPGEDESLEELSHYYASLCHYLNVVTRQWWEGADMW
Length: 47(24-70)
Propeptide: MVSVCRPWPAVAIALLALLVCLGALVDTCPIKPEAPGEDESLEELSHYYASLCHYLNVVTRQWWEGADMW
Signal peptide: MVSVCRPWPAVAIALLALLVCLG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005494_AF2.pdb

hor005494_ESM.pdb

Mass:	627475	Formula:	C245H356N60O76S3
Absent amino acids:	F	Common amino acids:	E
pI:	3.99	Basic residues:	4
Polar residues:	13	Hydrophobic residues:	16
Hydrophobicity:	-40.64	Boman Index:	-6209
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	76.81
Instability Index:	5737.87	Extinction Coefficient cystines:	21095
Absorbance 280nm:	458.59