General Information

  • ID:  hor005077
  • Uniprot ID:  P82697
  • Protein name:  Peptide hormone 4
  • Gene name:  NA
  • Organism:  Periplaneta americana (American cockroach) (Blatta americana)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Periplaneta (genus), Blattinae (subfamily), Blattidae (family), Blattoidea (superfamily), Blattodea (order), Dictyoptera (superorder), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  TDPLWQLPGAHLEQYLS
  • Length:  17(1-17)
  • Propeptide:  TDPLWQLPGAHLEQYLS
  • Signal peptide:  NA
  • Modification:  T17 Serine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-P82697-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    AF-P82697-F1.pdbhor005077_AF2.pdbhor005077_ESM.pdb

Physical Information

Mass: 225378 Formula: C91H134N22O27
Absent amino acids: CFIKMNRV Common amino acids: L
pI: 4.18 Basic residues: 1
Polar residues: 4 Hydrophobic residues: 6
Hydrophobicity: -44.12 Boman Index: -1262
Half-Life: 7.2 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 97.65
Instability Index: 3157.65 Extinction Coefficient cystines: 6990
Absorbance 280nm: 436.88

Literature

  • PubMed ID:  10676456
  • Title:  The unique neuropeptide pattern in abdominal perisympathetic organs of insects.