HORDB

ID: hor005019
Uniprot ID: P04561
Protein name: Urotensin II-beta
Gene name: NA
Organism: Cyprinus carpio (Common carp)
Family: Urotensin-2 family
Source: animal
Expression: teleost caudal neurosecretory system
Disease: NA
Comments: NA
Taxonomy: Cyprinus (genus), Cyprininae (subfamily), Cyprinidae (family), Cyprinoidei (suborder), Cypriniformes (order), Cypriniphysae (superorder), Otophysi, Ostariophysi (subcohort), Otomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction; GO:0008217 regulation of blood pressure; GO:0097746 blood vessel diameter maintenance
GO CC: GO:0005576 extracellular region

Function: It has a suggested role in osmoregulation and as a corticotropin-releasing factor.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005019_AF2.pdb

hor005019_ESM.pdb

Mass:	160298	Formula:	C63H87N15O18S2
Absent amino acids:	ADHILMPQRS	Common amino acids:	CG
pI:	6.13	Basic residues:	1
Polar residues:	7	Hydrophobic residues:	3
Hydrophobicity:	-21.67	Boman Index:	-792
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	24.17
Instability Index:	5168.33	Extinction Coefficient cystines:	7115
Absorbance 280nm:	646.82