General Information

  • ID:  hor004827
  • Uniprot ID:  P13736
  • Protein name:  Contraction-inhibiting peptide 1
  • Gene name:  N/A
  • Organism:  Mytilus edulis (Blue mussel)
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Mytilus (genus), Mytilinae (subfamily), Mytilidae (family), Mytiloidea (superfamily), Mytilida (order), Pteriomorphia, Autobranchia (subclass), Bivalvia (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005179 hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  NA

Sequence Information

  • Sequence:  GSPMFV
  • Length:  6(1-6)
  • Propeptide:  GSPMFV
  • Signal peptide:  NA
  • Modification:  T6 Valine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Inhibitory action on contractions in several molluscan muscles.
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004827_AF2.pdbhor004827_ESM.pdb

Physical Information

Mass: 72612 Formula: C29H44N6O8S
Absent amino acids: ACDEHIKLNQRTWY Common amino acids: FGMPSV
pI: 6.11 Basic residues: 0
Polar residues: 2 Hydrophobic residues: 2
Hydrophobicity: 101.67 Boman Index: 691
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 48.33
Instability Index: 6900 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  3377776
  • Title:  Structures and actions of Mytilus inhibitory peptides.