HORDB

ID: hor004823
Uniprot ID: P58648
Protein name: Cardioactive peptide Ocp-1/Ocp-2
Gene name: N/A
Organism: Callistoctopus minor (Octopus) (Octopus minor)
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Callistoctopus (genus), Octopodidae (family), Incirrata (suborder), Octopoda (order), Octopodiformes (superorder), Coleoidea (subclass), Cephalopoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Function: Cardioactive; has both positive chronotropic and inotropic effects on the heart. Ocp-2 is a 1000 time less active than Ocp-1.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004823_AF2.pdb

hor004823_ESM.pdb

Mass:	44808	Formula:	C17H22N4O7
Absent amino acids:	ACEHIKLMNPQRSTVWY	Common amino acids:	G
pI:	3.75	Basic residues:	0
Polar residues:	2	Hydrophobic residues:	1
Hydrophobicity:	-37.5	Boman Index:	-386
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	0
Instability Index:	750	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 10876044
Title: Cardioactive peptides isolated from the brain of a Japanese octopus, Octopus minor.