General Information

  • ID:  hor004758
  • Uniprot ID:  Q8LAX3
  • Protein name:  Elicitor peptide 3
  • Gene name:  PEP3
  • Organism:  Arabidopsis thaliana (Mouse-ear cress)
  • Family:  Brassicaceae elicitor peptide family
  • Source:  Plant
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Arabidopsis (genus), Camelineae (tribe), Brassicaceae (family), Brassicales (order), malvids, rosids, Pentapetalae, Gunneridae, eudicotyledons, Mesangiospermae, Magnoliopsida (class), Spermatophyta, Euphyllophyta, Tracheophyta, Embryophyta, Streptophytina (subphylum), Streptophyta (phylum), Viridiplantae (kingdom), Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0006952 defense response; GO:0045087 innate immune response; GO:0071456 cellular response to hypoxia
  • GO CC:  NA

Sequence Information

  • Sequence:  EIKARGKNKTKPTPSSGKGGKHN
  • Length:  23(74-96)
  • Propeptide:  MENLRNGEDNGSLIPFTFFDQSSVTIPLLKCSGLESSSSSSSSCDLSSSHSEEDESIDIKEEEEEEEEDGMTIEIKARGKNKTKPTPSSGKGGKHN
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  plays a significant role in both salinity stress tolerance and immune response
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-Q8LAX3-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004758_AF2.pdbhor004758_ESM.pdb

Physical Information

Mass: 281333 Formula: C102H178N36O32
Absent amino acids: CDFLMQVWY Common amino acids: K
pI: 11.46 Basic residues: 8
Polar residues: 10 Hydrophobic residues: 2
Hydrophobicity: -187.39 Boman Index: -7442
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 21.3
Instability Index: 3521.74 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  29760074
  • Title:  AtPep3 is a hormone-like peptide that plays a role in the salinity stress tolerance of plants.