General Information

  • ID:  hor004698
  • Uniprot ID:  Q8LE92
  • Protein name:  Tyrosine-sulfated glycopeptide 2
  • Gene name:  PSY2
  • Organism:  Arabidopsis thaliana (Mouse-ear cress)
  • Family:  Sulfated-peptide plant hormone family
  • Source:  Plant
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Arabidopsis (genus), Camelineae (tribe), Brassicaceae (family), Brassicales (order), malvids, rosids, Pentapetalae, Gunneridae, eudicotyledons, Mesangiospermae, Magnoliopsida (class), Spermatophyta, Euphyllophyta, Tracheophyta, Embryophyta, Streptophytina (subphylum), Streptophyta (phylum), Viridiplantae (kingdom), Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0003674 molecular_function; GO:0008083 growth factor activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  DYDDPSANTRHDPSVPTN
  • Length:  18
  • Propeptide:  MSFGTRLLLFLILTLPLVTSSSPNTLHVSGIVKTGTTSRFLMMTIEDYDDPSANTRHDPSVPTNAKADTTP
  • Signal peptide:  MSFGTRLLLFLILTLPLVTS
  • Modification:  T2 Sulfotyrosine;T16 4-hydroxyproline
  • Glycosylation:  T16 O-linked (Ara...) hydroxyproline
  • Mutagenesis:  NA

Activity

  • Function:  Promotes cellular proliferation and expansion.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-Q8LE92-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004698_AF2.pdbhor004698_ESM.pdb

Physical Information

Mass: 230441 Formula: C82H121N25O34
Absent amino acids: CEFGIKLMQW Common amino acids: D
pI: 4.02 Basic residues: 2
Polar residues: 7 Hydrophobic residues: 2
Hydrophobicity: -176.67 Boman Index: -7397
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 21.67
Instability Index: 5233.33 Extinction Coefficient cystines: 1490
Absorbance 280nm: 87.65

Literature

  • PubMed ID:  NA
  • Title:  NA