HORDB

ID: hor004674
Uniprot ID: Q6ID76
Protein name: Root meristem growth factor 3
Gene name: GLV7
Organism: Arabidopsis thaliana (Mouse-ear cress)
Family: RGF family
Source: Plant
Expression: In roots, expressed only in the quiescent center (QC), the columella stem cells (CC) and the innermost layer of central columella cells; mostly present in the third and fourth CC layers, but not, or only marginally, in the QC . |Expressed in root tips .
Disease: NA
Comments: NA
Taxonomy: Arabidopsis (genus), Camelineae (tribe), Brassicaceae (family), Brassicales (order), malvids, rosids, Pentapetalae, Gunneridae, eudicotyledons, Mesangiospermae, Magnoliopsida (class), Spermatophyta, Euphyllophyta, Tracheophyta, Embryophyta, Streptophytina (subphylum), Streptophyta (phylum), Viridiplantae (kingdom), Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005515 protein binding; GO:0008083 growth factor activity
GO BP: GO:0007165 signal transduction; GO:0008284 positive regulation of cell population proliferation; GO:0009786 regulation of asymmetric cell division; GO:0010082 regulation of root meristem growth; GO:0010628 positive regulation of gene expression; GO:0030154 cell differentiation; GO:2000023 regulation of lateral root development; GO:2000067 regulation of root morphogenesis
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: DYWRAKHHPPKNN
Length: 13
Propeptide: MTTLSKILCVLIILLLCFSFRYSLHEDGNQQSSRDFVSTAKAIKYGDVMKKMIRGRKLMMASGEKEEAETKMKRGNRETERNSSKSVEEDGLVAYTADYWRAKHHPPKNN
Signal peptide: MTTLSKILCVLIILLLCFSFRYS
Modification: T2 Sulfotyrosine;T10 Hydroxyproline
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004674_AF2.pdb

hor004674_ESM.pdb

Mass:	187705	Formula:	C75H107N25O19
Absent amino acids:	CEFGILMQSTV	Common amino acids:	HKNP
pI:	10.24	Basic residues:	5
Polar residues:	3	Hydrophobic residues:	2
Hydrophobicity:	-252.31	Boman Index:	-5334
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	7.69
Instability Index:	1385.38	Extinction Coefficient cystines:	6990
Absorbance 280nm:	582.5