HORDB

ID: hor004663
Uniprot ID: Q3EDH8
Protein name: CLAVATA3/ESR (CLE)-related protein 3
Gene name: CLE3
Organism: Arabidopsis thaliana (Mouse-ear cress)
Family: CLV3/ESR signal peptide family
Source: Plant
Expression: [CLE3p]: Mostly expressed in roots, stems and apex, and, to a lower extent, in seedlings, leaves, flowers, siliques and pollen.
Disease: NA
Comments: NA
Taxonomy: Arabidopsis (genus), Camelineae (tribe), Brassicaceae (family), Brassicales (order), malvids, rosids, Pentapetalae, Gunneridae, eudicotyledons, Mesangiospermae, Magnoliopsida (class), Spermatophyta, Euphyllophyta, Tracheophyta, Embryophyta, Streptophytina (subphylum), Streptophyta (phylum), Viridiplantae (kingdom), Eukaryota (superkingdom), cellular organisms
GO MF: GO:0033612 receptor serine/threonine kinase binding
GO BP: GO:0030154 cell differentiation; GO:0045168 cell-cell signaling involved in cell fate commitment
GO CC: GO:0005576 extracellular region; GO:0048046 apoplast

Sequence: RPLVAEERFSGSSRLKKIRRELFERLKEMKGRSEGEETILGNTLDSKRLSPGGPDPRHH
Length: 59(25-83)
Propeptide: MASLKLWVCLVLLLVLELTSVHECRPLVAEERFSGSSRLKKIRRELFERLKEMKGRSEGEETILGNTLDSKRLSPGGPDPRHH
Signal peptide: MASLKLWVCLVLLLVLELTSVHEC
Modification: T51 Hydroxyproline;T54 Hydroxyproline
Glycosylation: T54 O-linked (Ara...) hydroxyproline
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004663_AF2.pdb

hor004663_ESM.pdb

Mass:	782037	Formula:	C291H486N96O89S
Absent amino acids:	CQWY	Common amino acids:	RE
pI:	10.9	Basic residues:	16
Polar residues:	15	Hydrophobic residues:	13
Hydrophobicity:	-120	Boman Index:	-21137
Half-Life:	1 hour	Half-Life Yeast:	2 min
Half-Life E.Coli:	2 min	Aliphatic Index	66.1
Instability Index:	6348.47	Extinction Coefficient cystines:	0
Absorbance 280nm:	0