HORDB

ID: hor004605
Uniprot ID: Q9I980
Protein name: Thymosin beta-10
Gene name: NA
Organism: Torpedo marmorata (Marbled electric ray)
Family: Thymosin beta family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Torpedo (genus), Torpedinidae (family), Torpediniformes (order), Batoidea (superorder), Elasmobranchii (subclass), Chondrichthyes (class), Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0003779 actin binding; GO:0003785 actin monomer binding
GO BP: GO:0007015 actin filament organization
GO CC: GO:0005737 cytoplasm; GO:0005856 cytoskeleton

Function: Plays an important role in the organization of the cytoskeleton.
Mechanism: Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004605_AF2.pdb

hor004605_ESM.pdb

Mass:	553461	Formula:	C207H340N54O75
Absent amino acids:	CHMRWY	Common amino acids:	K
pI:	4.98	Basic residues:	9
Polar residues:	11	Hydrophobic residues:	10
Hydrophobicity:	-130	Boman Index:	-13106
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	47.67
Instability Index:	1200.7	Extinction Coefficient cystines:	0
Absorbance 280nm:	0