General Information

  • ID:  hor004493
  • Uniprot ID:  P40752
  • Protein name:  Urechistachykinin-2
  • Gene name:  NA
  • Organism:  Urechis unicinctus (Fat innkeeper worm) (Chinese penis fish)
  • Family:  Tachykinin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Urechis (genus), Urechidae (family), Xenopneusta (order), Echiura (subclass), Polychaeta (class), Annelida (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  AAGMGFFGAR
  • Length:  10(1-10)
  • Propeptide:  AAGMGFFGAR
  • Signal peptide:  NA
  • Modification:  T10 Arginine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Contractile action on the inner circular body-wall muscle of the animal.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004493_AF2.pdbhor004493_ESM.pdb

Physical Information

Mass: 114486 Formula: C44H65N13O11S
Absent amino acids: CDEHIKLNPQSTVWY Common amino acids: AG
pI: 10.55 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 5
Hydrophobicity: 72 Boman Index: 164
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 30
Instability Index: 51 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  8476410
  • Title:  Two novel tachykinin-related neuropeptides in the echiuroid worm, Urechis unicinctus.