HORDB

ID: hor004488
Uniprot ID: Q7LZ48
Protein name: Des[Ser(1)Pro(2)] scyliorhinin-2
Gene name: NA
Organism: Torpedo marmorata (Marbled electric ray)
Family: Tachykinin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Torpedo (genus), Torpedinidae (family), Torpediniformes (order), Batoidea (superorder), Elasmobranchii (subclass), Chondrichthyes (class), Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Function: Excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-Q7LZ48-F1.pdb

hor004488_AF2.pdb

hor004488_ESM.pdb

Mass:	193764	Formula:	C69H108N18O24S3
Absent amino acids:	AEHIQRTWY	Common amino acids:	CDGPS
pI:	4.11	Basic residues:	1
Polar residues:	7	Hydrophobic residues:	3
Hydrophobicity:	-14.38	Boman Index:	-1770
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	42.5
Instability Index:	611.88	Extinction Coefficient cystines:	125
Absorbance 280nm:	8.33

PubMed ID: 2847952
Title: Isolation of the Tachykinin, des[Ser1Pro2]scyliorhinin II From the Intestine of the Ray, Torpedo Marmorata