General Information

  • ID:  hor004377
  • Uniprot ID:  B3EWM6
  • Protein name:  Tachykinin-related peptide GLGNNAFLGVR-amide
  • Gene name:  NA
  • Organism:  Delia radicum (Cabbage root fly) (Anthomyia brassicae)
  • Family:  Tachykinin family
  • Source:  Animal
  • Expression:  Detected in larvae. |Expressed in the CNS and midgut but not in the ring gland, thoracic perisympathetic organs (tPSO) and abdominal perisympathetic organs (aPSO) (at protein level).
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Delia (genus), Anthomyiinae (subfamily), Anthomyiidae (family), Muscoidea (superfamily), Calyptratae, Schizophora, Cyclorrhapha, Eremoneura, Muscomorpha (infraorder), Brachycera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  GLGNNAFLGVR
  • Length:  11(1-11)
  • Propeptide:  GLGNNAFLGVR
  • Signal peptide:  NA
  • Modification:  T11 Arginine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myoactive peptide
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-Q96A98-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    AF-Q96A98-F1.pdbhor004377_AF2.pdbhor004377_ESM.pdb

Physical Information

Mass: 129583 Formula: C49H80N16O14
Absent amino acids: CDEHIKMPQSTWY Common amino acids: G
pI: 10.55 Basic residues: 1
Polar residues: 5 Hydrophobic residues: 5
Hydrophobicity: 33.64 Boman Index: -671
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 106.36
Instability Index: 137.27 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  22848525
  • Title:  Peptidomics of the Agriculturally Damaging Larval Stage of the Cabbage Root Fly Delia Radicum (Diptera: Anthomyiidae)