General Information

  • ID:  hor004253
  • Uniprot ID:  NA
  • Protein name:  bufokinin
  • Gene name:  NA
  • Organism:  Bufo marinus
  • Family:  Tachykinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  KPRPDQFYGLM
  • Length:  11
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T11 Methionine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: 0.34nM
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004253_AF2.pdbhor004253_ESM.pdb

Physical Information

Mass: 153013 Formula: C62H94N16O16S
Absent amino acids: ACEHINSTVW Common amino acids: P
pI: 9.3 Basic residues: 2
Polar residues: 2 Hydrophobic residues: 2
Hydrophobicity: -107.27 Boman Index: -2368
Half-Life: 1.3 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 35.45
Instability Index: 2110 Extinction Coefficient cystines: 1490
Absorbance 280nm: 149

Literature

  • PubMed ID:  15627485
  • Title:  Quantitative Structure-Activity Analyses of Bufokinin and Other Tachykinins at Bufokinin (bNK1) Receptors of the Small Intestine of the Cane Toad, Bufo Marinus