General Information

  • ID:  hor004178
  • Uniprot ID:  NA
  • Protein name:  Angiotensin II
  • Gene name:  NA
  • Organism:  NA
  • Family:  Serpin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  RVYVHPF
  • Length:  7
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Regulate blood pressure
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004178_AF2.pdbhor004178_ESM.pdb

Physical Information

Mass: 102427 Formula: C45H64N12O9
Absent amino acids: ACDEGIKLMNQSTW Common amino acids: V
pI: 9.35 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 3
Hydrophobicity: 8.57 Boman Index: -866
Half-Life: 1 hour Half-Life Yeast: 2 min
Half-Life E.Coli: 2 min Aliphatic Index 82.86
Instability Index: 2120 Extinction Coefficient cystines: 1490
Absorbance 280nm: 248.33

Literature

  • PubMed ID:  214562
  • Title:  Photoaffinity Labeling of the Angiotensin II Receptor. 1. Synthesis and Biological Activities of the Labeling Peptides