General Information

  • ID:  hor004173
  • Uniprot ID:  NA
  • Protein name:  Angiotensin II
  • Gene name:  NA
  • Organism:  NA
  • Family:  Serpin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  DRVYIHPFHL
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Regulate blood pressure
  • Mechanism:  NA
  • Cross BBB:  YES
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: 1 hours; /3600 seconds ( PubMed ID: 22186872 )

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004173_AF2.pdbhor004173_ESM.pdb

Physical Information

Mass: 145721 Formula: C62H89N17O14
Absent amino acids: ACEGKMNQSTW Common amino acids: H
pI: 7.71 Basic residues: 3
Polar residues: 1 Hydrophobic residues: 4
Hydrophobicity: -20 Boman Index: -1624
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 107
Instability Index: 2264 Extinction Coefficient cystines: 1490
Absorbance 280nm: 165.56

Literature

  • PubMed ID:  9149430##22186872
  • Title:  Profiling Peptide Adducts of Oxidized N-acetyldopamine by Electrospray Mass Spectrometry