HORDB

ID: hor004055
Uniprot ID: P09971
Protein name: Diapause hormone
Gene name: NA
Organism: Bombyx mori (Silk moth)
Family: Pyrokinin family
Source: Animal
Expression: Expression is restricted to the subesophageal ganglion.
Disease: NA
Comments: NA
Taxonomy: Bombyx (genus), Bombycinae (subfamily), Bombycidae (family), Bombycoidea (superfamily), Obtectomera, Ditrysia, Heteroneura (parvorder), Neolepidoptera (infraorder), Glossata (suborder), Lepidoptera (order), Amphiesmenoptera (superorder), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity; GO:0016084 myostimulatory hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0042811 pheromone biosynthetic process
GO CC: GO:0005576 extracellular region

Sequence: TDMKDESDRGAHSERGALWFGPRL
Length: 24(24-47)
Propeptide: MYKTNIVFNVLALALFSIFFASCTDMKDESDRGAHSERGALWFGPRLGKRSMKPSTEDNRQTFLRLLEAADALKFYYDQLPYERQADEPETKVTKKIIFTPKLGRSVAKPQTHESLEFIPRLGRRLSEDMPATPADQEMYQPDPEEMESRTRYFSPRLGRTMSFSPRLGRELSYDYPTKYRVARSVNKTMDN
Signal peptide: MYKTNIVFNVLALALFSIFFASC
Modification: T24 Leucine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004055_AF2.pdb

hor004055_ESM.pdb

Mass:	314241	Formula:	C116H179N37O38S
Absent amino acids:	CINQVY	Common amino acids:	DGR
pI:	5.63	Basic residues:	5
Polar residues:	6	Hydrophobic residues:	6
Hydrophobicity:	-117.5	Boman Index:	-8018
Half-Life / Aliphatic Index:	7.2 hour	Aliphatic Index:	40.83
Instability Index:	1152.92	Extinction Coefficient cystines:	5500
Absorbance 280nm:	239.13