HORDB

ID: hor004027
Uniprot ID: A0A7M6UV78
Protein name: Pyrokinin-1
Gene name: 100313507
Organism: Nasonia vitripennis (Parasitic wasp)
Family: Pyrokinin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Nasonia (genus), Pteromalinae (subfamily), Pteromalidae (family), Chalcidoidea (superfamily), Parasitoida (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: QYDGRGSDMVEGPRVERMHPETSGGCVGAHCLTQNSEGPVGAMWFGPRL
Length: 49(32-80)
Propeptide: MELARLINGARTKAILCALLVIVLMANRVAGQYDGRGSDMVEGPRVERMHPETSGGCVGAHCLTQNSEGPVGAMWFGPRLGRRRRSDKFTPKKIEALSEMLGSPNWNLVTIPGGEDKRQETTFTPRLGRELENAISVYDLVRGLVSSVDDQNGKDRDQQAPPPMFPPRLGRTLLTPRLEHELRNLLRKLQMQ
Signal peptide: MELARLINGARTKAILCALLVIVLMANRVAG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004027_AF2.pdb

hor004027_ESM.pdb

Mass:	611720	Formula:	C221H341N69O71S5
Absent amino acids:	IK	Common amino acids:	G
pI:	5.53	Basic residues:	6
Polar residues:	18	Hydrophobic residues:	10
Hydrophobicity:	-62.04	Boman Index:	-9388
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	43.67
Instability Index:	2531.43	Extinction Coefficient cystines:	7115
Absorbance 280nm:	148.23

PubMed ID: 20695486
Title: Genomics and Peptidomics of Neuropeptides and Protein Hormones Present in the Parasitic Wasp Nasonia Vitripennis