General Information

  • ID:  hor003994
  • Uniprot ID:  C3TWQ8
  • Protein name:  Pheromone biosynthesis activating neuropeptide
  • Gene name:  NA
  • Organism:  Solenopsis invicta (Red imported fire ant) (Solenopsis wagneri)
  • Family:  Pyrokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Solenopsis (genus), Solenopsidini (tribe), Myrmicinae (subfamily), Formicidae (family), Formicoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  GSGEDLSYGDAYEVDEDDHPLFVPRL
  • Length:  26
  • Propeptide:  MIVTRNSVNRATIVCIMAMLLCLGSRASGEYESREIGSNGGSSESRSPSNDFGSCIDGKCIKRTSQDIASGMWFGPRLGKRYKSDEKQELSSEIEILANALDGVRWAVITIPASDKRQPQFTPRLGRGSGEDLSYGDAYEVDEDDHPLFVPRLGRRLPWIPSPRLGRQLRNVLRKL
  • Signal peptide:  MIVTRNSVNRATIVCIMAMLLCLGSRASG
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-C3TWQ8-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003994_AF2.pdbhor003994_ESM.pdb

Physical Information

Mass: 334214 Formula: C127H183N31O47
Absent amino acids: CIKMNQTW Common amino acids: D
pI: 3.62 Basic residues: 2
Polar residues: 7 Hydrophobic residues: 7
Hydrophobicity: -76.54 Boman Index: -6024
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 71.15
Instability Index: 1298.46 Extinction Coefficient cystines: 2980
Absorbance 280nm: 119.2

Literature

  • PubMed ID:  19320757
  • Title:  Identification of a New Member of the PBAN Family of Neuropeptides From the Fire Ant, Solenopsis Invicta