General Information

  • ID:  hor003993
  • Uniprot ID:  NA
  • Protein name:  Leucopyrokinin
  • Gene name:  NA
  • Organism:  Sarcophaga bullata
  • Family:  Pyrokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  QTSFTPRL
  • Length:  8
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Accelerates pupariation in wandering larvae of the fleshfly Sarcophaga bullata
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003993_AF2.pdbhor003993_ESM.pdb

Physical Information

Mass: 107410 Formula: C42H68N12O13
Absent amino acids: ACDEGHIKMNVWY Common amino acids: T
pI: 10.55 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 2
Hydrophobicity: -65 Boman Index: -2110
Half-Life: 0.8 hour Half-Life Yeast: 10 min
Half-Life E.Coli: >10 hour Aliphatic Index 48.75
Instability Index: -67.5 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  12770042
  • Title:  Mode of Action of an Insect Neuropeptide Leucopyrokinin (LPK) on Pupariation in Fleshfly (Sarcophaga Bullata) Larvae (Diptera: Sarcophagidae)