General Information

  • ID:  hor003549
  • Uniprot ID:  A0A0L0CIT3
  • Protein name:  CAPA-Periviscerokinin-1
  • Gene name:  NA
  • Organism:  Lucilia cuprina (Green bottle fly) (Australian sheep blowfly)
  • Family:  Periviscerokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Lucilia (genus), Luciliinae (subfamily), Calliphoridae (family), Oestroidea (superfamily), Calyptratae, Schizophora, Cyclorrhapha, Eremoneura, Muscomorpha (infraorder), Brachycera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  GGGGSSGLFAFPRV
  • Length:  14
  • Propeptide:  MKSFNSVDFVMCSLVVIAIVGSSKAELEQTKNRRGGGGSSGLFAFPRVGRSDPSLNINNLHNPDVTADNAAAAAAAALDVLYPSSSFEEYEEYPKSDVKRGGLIAYPRIGRSDADVRKWARLMALQQALDKRTGPSATTGVWFGPRLGKRSVDNQQYEKPSGQKEEY
  • Signal peptide:  MKSFNSVDFVMCSLVVIAIVGSSKA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A0L0CIT3-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003549_AF2.pdbhor003549_ESM.pdb

Physical Information

Mass: 154051 Formula: C59H89N17O17
Absent amino acids: CDEHIKMNQTWY Common amino acids: G
pI: 10.55 Basic residues: 1
Polar residues: 7 Hydrophobic residues: 5
Hydrophobicity: 40.71 Boman Index: -29
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 55.71
Instability Index: 5785.71 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  23280433
  • Title:  Neuropeptidomics of the Australian Sheep Blowfly Lucilia Cuprina (Wiedemann) and Related Diptera