General Information

  • ID:  hor003543
  • Uniprot ID:  E9G007
  • Protein name:  Periviscerokinin-1
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  Periviscerokinin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  APPQILKSQSLIPFPRV
  • Length:  17(22-38)
  • Propeptide:  MRIAIIHSLVLVVIYLAYSDAAPPQILKSQSLIPFPRVGRSRSSFIANAVGSARSGGAGNPMMMGSGGNANGKSPNNWMMNNADIKRHLIPFPRVGKRQNLIPFPRVGRAGYYQPGFFPSTDDEEGQASIQQQFALSSEESQASAPSSFLMSGSDILGALNNGRSNSDERTAVFIPRRWMTNSQESEE
  • Signal peptide:  MRIAIIHSLVLVVIYLAYSDA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9G007-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003543_AF2.pdbhor003543_ESM.pdb

Physical Information

Mass: 217685 Formula: C89H147N23O22
Absent amino acids: CDEGHMNTWY Common amino acids: P
pI: 11.65 Basic residues: 2
Polar residues: 2 Hydrophobic residues: 7
Hydrophobicity: 11.76 Boman Index: -984
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 114.71
Instability Index: 10344.12 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones