General Information

  • ID:  hor003408
  • Uniprot ID:  E9HBU8
  • Protein name:  Orcomyotropin-like peptide 1
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  Orcokinin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005184 neuropeptide hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  NA

Sequence Information

  • Sequence:  LDSLTGLGFGSQ
  • Length:  12(91-102)
  • Propeptide:  MNCLKFRLVAVAILIFNVVTALNYQSEEAVGVEHERDRDSLGGGHILRGLDSIGESNLLRAIYREKPRDFLRINRGLDSLSGASFGIEKRLDSLTGLGFGSQKRNLDEIDRSNFGTFAKRNLDEIDRSDFGRFVKKRETMEAESSQQQH
  • Signal peptide:  MNCLKFRLVAVAILIFNVVTA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9HBU8-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003408_AF2.pdbhor003408_ESM.pdb

Physical Information

Mass: 139070 Formula: C52H83N13O19
Absent amino acids: ACEHIKMNPRVWY Common amino acids: GL
pI: 3.75 Basic residues: 0
Polar residues: 6 Hydrophobic residues: 4
Hydrophobicity: 30.83 Boman Index: -307
Half-Life / Aliphatic Index: 5.5 hour Aliphatic Index: 97.5
Instability Index: 3419.17 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones