HORDB

General Information

ID: hor003221
Uniprot ID: NA
Protein name: Leu-Val-Val-hemorphin-7
Gene name: NA
Organism: NA
Family: Opioid neuropeptide precursor family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: LVVYPWTQRY
Length: 10
Propeptide: NA
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Activity

Function: NA
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
Kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor003221_AF2.pdb

hor003221_ESM.pdb

Physical Information

Mass:	148525	Formula:	C65H93N15O15
Absent amino acids:	ACDEFGHIKMNS	Common amino acids:	VY
pI:	9.17	Basic residues:	1
Polar residues:	3	Hydrophobic residues:	4
Hydrophobicity:	-16	Boman Index:	-798
Half-Life / Aliphatic Index:	5.5 hour	Aliphatic Index:	97
Instability Index:	-1919	Extinction Coefficient cystines:	8480
Absorbance 280nm:	942.22

Literature

PubMed ID: 14499287
Title: Kinetic-controlled Hydrolysis of Leu-Val-Val-hemorphin-7 Catalyzed by Angiotensin-Converting Enzyme From Rat Brain