General Information

  • ID:  hor003218
  • Uniprot ID:  NA
  • Protein name:  Endomorphin-2
  • Gene name:  NA
  • Organism:  NA
  • Family:  Opioid neuropeptide precursor family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  YPFF
  • Length:  4
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T4 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003218_AF2.pdbhor003218_ESM.pdb

Physical Information

Mass: 62634 Formula: C32H36N4O6
Absent amino acids: ACDEGHIKLMNQRSTVW Common amino acids: F
pI: 6.09 Basic residues: 0
Polar residues: 1 Hydrophobic residues: 2
Hydrophobicity: 67.5 Boman Index: 582
Half-Life / Aliphatic Index: 2.8 hour Aliphatic Index: 0
Instability Index: 8650 Extinction Coefficient cystines: 1490
Absorbance 280nm: 496.67

Literature

  • PubMed ID:  17492626
  • Title:  Colocalization and Shared Distribution of Endomorphins With Substance P, Calcitonin Gene-Related Peptide, Gamma-Aminobutyric Acid, and the Mu opioid neuropeptide precursor family Receptor