General Information

  • ID:  hor003055
  • Uniprot ID:  NA
  • Protein name:  Neurotensin
  • Gene name:  NA
  • Organism:  Bufo marinus
  • Family:  Neurotensin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EAIVSKARRPYIL
  • Length:  13
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T1 Pyrrolidone carboxylic acid
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Contractile activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003055_AF2.pdbhor003055_ESM.pdb

Physical Information

Mass: 173004 Formula: C69H118N20O18
Absent amino acids: CDFGHMNQTW Common amino acids: AIR
pI: 10.45 Basic residues: 3
Polar residues: 2 Hydrophobic residues: 6
Hydrophobicity: 3.85 Boman Index: -2332
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 127.69
Instability Index: 7639.23 Extinction Coefficient cystines: 1490
Absorbance 280nm: 124.17

Literature

  • PubMed ID:  9786176
  • Title:  Purification, Characterization, and Spasmogenic Activity of Neurotensin From the Toad Bufo Marinus