General Information

  • ID:  hor003037
  • Uniprot ID:  NA
  • Protein name:  Neuropeptide B
  • Gene name:  NPB
  • Organism:  NA
  • Family:  Neuropeptide B/W family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  WYKPAAGHSSYSVGRAAGLLSGL
  • Length:  23
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003037_AF2.pdbhor003037_ESM.pdb

Physical Information

Mass: 274124 Formula: C107H162N30O30
Absent amino acids: CDEFIMNQT Common amino acids: AGS
pI: 10.01 Basic residues: 3
Polar residues: 10 Hydrophobic residues: 9
Hydrophobicity: 5.65 Boman Index: -688
Half-Life: 2.8 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 80.87
Instability Index: 1934.35 Extinction Coefficient cystines: 8480
Absorbance 280nm: 385.45

Literature

  • PubMed ID:  15918679
  • Title:  NMR Conformational Analyses on (Des-Bromo) Neuropeptide B [1-23] and Neuropeptide W [1-23]: The Importance of Alpha-Helices, a Cation-Pi Interaction and a Beta-Turn