HORDB

ID: hor002888
Uniprot ID: Q09367
Protein name: Neuropeptide-like peptide 11
Gene name: nlp-11
Organism: Caenorhabditis elegans
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: SPAISPAYQFENAFGLSEALERA
Length: 23(109-131)
Propeptide: MMSTLALVSLAIFGIAVVCAAPKPATVPVANEEDYLAALYGFEAPGSQFKGAPLQSKRHISPSYDVEIDAGNMRNLLDIGKRSAPMASDYGNQFQMYNRLIDAGKKKRSPAISPAYQFENAFGLSEALERAGRR
Signal peptide: MMSTLALVSLAIFGIAVVCA
Modification: T23 Alanine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-P61278-F1.pdb

hor002888_AF2.pdb

hor002888_ESM.pdb

Mass:	286129	Formula:	C111H166N28O36
Absent amino acids:	CDHKMTVW	Common amino acids:	A
pI:	3.98	Basic residues:	1
Polar residues:	6	Hydrophobic residues:	10
Hydrophobicity:	-11.3	Boman Index:	-2716
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	72.61
Instability Index:	6961.74	Extinction Coefficient cystines:	1490
Absorbance 280nm:	67.73

PubMed ID: 16061202
Title: Discovering Neuropeptides in Caenorhabditis Elegans by Two Dimensional Liquid Chromatography and Mass Spectrometry