General Information

  • ID:  hor002695
  • Uniprot ID:  H2KZL2
  • Protein name:  NLP-9
  • Gene name:  nlp-9
  • Organism:  Caenorhabditis elegans
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  GGGRAFNHNANLFRFD
  • Length:  16(77-92)
  • Propeptide:  MDRFATRFIALLLVLLQIGSIFATPIAEAQGAPEDVDDRRELEKRGGARAFYGFYNAGNSKRDQAAALPYYLYEKRGGGRAFNHNANLFRFDKRGGGRAFAGSWSPYLERFYDYKRSSYPVYFSDNSYY
  • Signal peptide:  MDRFATRFIALLLVLLQIGSIFA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-H2KZL2-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002695_AF2.pdbhor002695_ESM.pdb

Physical Information

Mass: 206067 Formula: C79H113N27O22
Absent amino acids: CEIKMPQSTVWY Common amino acids: FGN
pI: 10.4 Basic residues: 3
Polar residues: 6 Hydrophobic residues: 6
Hydrophobicity: -72.5 Boman Index: -4284
Half-Life / Aliphatic Index: 30 hour Aliphatic Index: 36.88
Instability Index: 4731.25 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  20013198
  • Title:  Approaches to Identify Endogenous Peptides in the Soil Nematode Caenorhabditis elegans