HORDB

ID: hor002655
Uniprot ID: Q9U2B9
Protein name: NLP-21
Gene name: nlp-21
Organism: Caenorhabditis elegans
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: QYTSELEEDE
Length: 10(23-32)
Propeptide: MRNSLFTTLFFGLAALVMVLNAQYTSELEEDEKRGGARAMLHKRGGARAFSADVGDDYKRGGARAFYDEKRGGARAFLTEMKRGGARVFQGFEDEKRGGARAFMMDKRGGGRAFGDMMKRGGARAFVENSKRDEDWVIRPFEDDRLGVF
Signal peptide: MRNSLFTTLFFGLAALVMVLNA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002655_AF2.pdb

hor002655_ESM.pdb

Mass:	140292	Formula:	C51H75N11O25
Absent amino acids:	ACFGHIKMNPRVW	Common amino acids:	E
pI:	3.26	Basic residues:	0
Polar residues:	3	Hydrophobic residues:	1
Hydrophobicity:	-200	Boman Index:	-4269
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	39
Instability Index:	6409	Extinction Coefficient cystines:	1490
Absorbance 280nm:	165.56

PubMed ID: 20013198
Title: Approaches to Identify Endogenous Peptides in the Soil Nematode Caenorhabditis elegans