General Information

  • ID:  hor002601
  • Uniprot ID:  A8X671
  • Protein name:  NLP-8
  • Gene name:  nlp-8
  • Organism:  Caenorhabditis briggsae
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0030431 sleep
  • GO CC:  NA

Sequence Information

  • Sequence:  SADPYRFMTVPT
  • Length:  12(86-97)
  • Propeptide:  MSQKLLSISPLRLLFLQCLLIGFAVSYPYLIFPASPSSGDSRRLVKRAFDRFDNSGVFSFGSKRFDRYEEENPYGYNFGAHIFKRSADPYRFMTVPTKKAFDRMDNSDFFGAKRKRSFDRMGGTEFGLMKRSAPEDREQLIDSLTDSILALRRARESESSGTTQPVAISYED
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A8X671-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002601_AF2.pdbhor002601_ESM.pdb

Physical Information

Mass: 158094 Formula: C62H93N15O19S
Absent amino acids: CEGHIKLNQW Common amino acids: PT
pI: 6.34 Basic residues: 1
Polar residues: 4 Hydrophobic residues: 3
Hydrophobicity: -33.33 Boman Index: -2114
Half-Life / Aliphatic Index: 1.9 hour Aliphatic Index: 32.5
Instability Index: 165 Extinction Coefficient cystines: 1490
Absorbance 280nm: 135.45

Literature

  • PubMed ID:  18760316
  • Title:  Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS