HORDB

ID: hor002585
Uniprot ID: A8Y1S8
Protein name: NLP-12
Gene name: nlp-12
Organism: Caenorhabditis briggsae
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0031739 cholecystokinin receptor binding
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0060756 foraging behavior
GO CC: GO:0043005 neuron projection; GO:0043025 neuronal cell body

Sequence: DGYRPLQF
Length: 8(42-49)
Propeptide: MLRNSCVLVLLILVFVDVFATQSPTFDRQDRDYRPLQFGKRDGYRPLQFGKRDYRPLQFGKRSGGGSVVLEPIWEWQ
Signal peptide: MLRNSCVLVLLILVFVDVFA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002585_AF2.pdb

hor002585_ESM.pdb

Mass:	112014	Formula:	C46H66N12O13
Absent amino acids:	ACEHIKMNSTVW	Common amino acids:	DFGLPQRY
pI:	6.34	Basic residues:	1
Polar residues:	2	Hydrophobic residues:	2
Hydrophobicity:	-102.5	Boman Index:	-2048
Half-Life / Aliphatic Index:	1.1 hour	Aliphatic Index:	48.75
Instability Index:	3240	Extinction Coefficient cystines:	1490
Absorbance 280nm:	212.86

PubMed ID: 18760316
Title: Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS