General Information

  • ID:  hor002555
  • Uniprot ID:  A0A7M7GM99
  • Protein name:  Neuropeptide like precursor 1
  • Gene name:  LOC100577694
  • Organism:  Apis mellifera (Honeybee)
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Apis (genus), Apini (tribe), Apinae (subfamily), Apidae (family), Apoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  GIFLPGSVILRALSRQ
  • Length:  16(367-382)
  • Propeptide:  MVEMAYIRKLTRTLPVLRFGEPHWEDISDLVCEMGLTGNHLVTLLLYVAVVNEIRLPLVTCQDEDSTQCMPKTAFLALLRHPEVSSSLAAYSRAARVTQDTKSRNDMAHLRALTEEGDDTEICVPGRVYLQLLKDPVVRGDLSAILNGRTQKVPDLLGRLIDDTDQMDAREYPFEYQKRSIATLAKNDDLPISLHDRMAENEDDEEKRAVISSSDHSIIRDYLPPNGRSEEQALRDFSMEKRNVGTLARDFALPP
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M7GM99-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002555_AF2.pdbhor002555_ESM.pdb

Physical Information

Mass: 199482 Formula: C79H135N23O20
Absent amino acids: CDEHKMNTWY Common amino acids: L
pI: 12.5 Basic residues: 2
Polar residues: 4 Hydrophobic residues: 8
Hydrophobicity: 79.38 Boman Index: -687
Half-Life / Aliphatic Index: 30 hour Aliphatic Index: 146.25
Instability Index: 6425.63 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  19576913
  • Title:  Mass Spectrometric Profiling of (Neuro)-Peptides in the Worker Honeybee, Apis Mellifera