General Information

  • ID:  hor002542
  • Uniprot ID:  NA
  • Protein name:  pedal peptide
  • Gene name:  NA
  • Organism:  Achatina fulica
  • Family:  NA
  • Source:  Animal
  • Expression:  central nervous system, locust subesophageal, thoracic, and abdominal ganglia
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  PLDSVYGTHGMSGFA
  • Length:  15
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Further modulatory actions of baratin in different circuits of the brain and ventral nerve cord
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002542_AF2.pdbhor002542_ESM.pdb

Physical Information

Mass: 178859 Formula: C68H99N17O22S
Absent amino acids: CEIKNQRW Common amino acids: G
pI: 5.29 Basic residues: 1
Polar residues: 7 Hydrophobic residues: 4
Hydrophobicity: 9.33 Boman Index: -397
Half-Life: >20 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: ? Aliphatic Index 52
Instability Index: 2820.67 Extinction Coefficient cystines: 1490
Absorbance 280nm: 106.43

Literature

  • PubMed ID:  10842231
  • Title:  Baratin, a Nonamidated Neurostimulating Neuropeptide, Isolated From Cockroach Brain: Distribution and Actions in the Cockroach and Locust Nervous Systems