HORDB

ID: hor002477
Uniprot ID: A0A6P6RHA0
Protein name: gGRN
Gene name: LOC113119378
Organism: Carassius auratus (Goldfish)
Family: Granulin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Carassius (genus), Cyprininae (subfamily), Cyprinidae (family), Cyprinoidei (suborder), Cypriniformes (order), Cypriniphysae (superorder), Otophysi, Ostariophysi (subcohort), Otomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: NA
GO CC: GO:0005576 extracellular region

Sequence: VIHCDSSTICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCLR
Length: 57(31-87)
Propeptide: MVPVLMLLMAALVAADEPMMALSEPAESVSVIHCDSSTICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCLRGWLRLPSSPKPATKAIQKPQSVSFDQALNWESQTEQVHCDGNVYCPTEQFCCKSATGQWGCCSEMVV
Signal peptide: MVPVLMLLMAALVAA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002477_AF2.pdb

hor002477_ESM.pdb

Mass:	732029	Formula:	C260H390N78O81S13
Absent amino acids:	AEKN	Common amino acids:	C
pI:	6.94	Basic residues:	8
Polar residues:	31	Hydrophobic residues:	9
Hydrophobicity:	-4.74	Boman Index:	-8175
Half-Life:	100 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	44.39
Instability Index:	5415.26	Extinction Coefficient cystines:	10720
Absorbance 280nm:	191.43

PubMed ID: 8536941
Title: Somatostatin-, Vasoactive Intestinal Peptide-, and Granulin-Like Peptides Isolated From Intestinal Extracts of Goldfish, Carassius Auratus